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Procera AVH Review
Procera AVH is dietary supplement advertised to improve brain function. It contains vinpocetine, huperzine A and acetyl-L-carnitine, all natural products proven to improve cognition and memory. It is even backed by a sponsored clinical study. But then there it attracted a class-action lawsuit and the heavy criticism of reviewers. Does Procera AVH work? Read on to find out.
Procera AVH is a nutritional supplement which the manufacturer claims can improve mental and enhance brain performance, memory and mood. It is widely reported to have been clinically proven to improve memory, cloudiness of consciousness (also known as brain or mental fog), mood, focus and concentration.
Procera AVH is said, by numerous users, to be the natural answer to absentmindedness, mental fog, incessant loss of attention, changes in mood, and mental weariness caused by insomnia, stress, ageing and even poor diet.
Procera AVH contains a patented mix of natural and active ingredients. The three distinctive and active ingredients of Procera AVH are vinpocetine, huperzine A and acetyl-l-carnitine (ALC).
Other inactive ingredients include stearic acid, croscarmellose sodium, magnesium stearate, microcrystalline cellulose, dicalcium phosphate, silica and film coating (hypromellose, hydroxypropyl cellulose, polyethylene glycol). Procera AVH does not contain stimulants.
Procera AVH is effective because it may swiftly re-establish the level of oxygen in the brain and acetylcholine, which is known to improve memory in the brain.
Acetylcholine is an important neurotransmitter in the brain and its production decreases with age. It is also the neurotransmitter mostly linked to memory and cognition.
Procera AVH works by boosting the flow of blood to the brain. As a result, it delivers more oxygen and important nutrients required for nutritional sustenance. This enhances the energy metabolism of brain cells and can improve the generation of new cells and the formation of new neural connections. The net result of all these improvements should improve mental focus, attentiveness, awareness, memory and other cognitive functions.
The suggested daily serving size is 2- 3 capsules taken at the same time with a meal or snack that preferably includes some fat. Procera AVH should not be taken on an empty stomach.
For those who desire increased mental energy in the morning, taking it with their breakfast is recommended. On the other hand, users who experience mental drifts during the day (and so desire a boost in mental energy) should take this supplement with their lunch or afternoon snack.
Procera AVH should not be administered to children under 18 years, pregnant women, lactating women and women who intend to get pregnant.
It is recommended that Procera AVH be taken daily because its benefits are cumulative. Daily usage should be sustained as continuous long-term supplementation.
There are no recognized adverse interactions, or contraindications with the ingredients in Procera AVH and other vitamins, minerals or herbs, but care should be taken when it is been used with other drugs.
Although, the effects of Procera AVH such as mental clarity are typically noticeable in the short term, the antioxidant, neuroprotective and other benefits for brain health take a while to become apparent. These benefits will, however, continue to increase with and should continue to increase with sustained with long term use.
The health claims of Procera AVH was investigated at one of the leading clinical trial sites in the world, the Brain Sciences Institute in Australia. The researchers there tested the supplement for its contribution towards improving cognitive health, function and performance.
Although Procera AVH is a dietary supplement, still the clinical trial made use of the FDA protocols for drug trials.
Such protocols includes a randomized, 30-day double-blind, placebo-controlled trial with an appreciable number of volunteers. The Procera AVH trial employed an ample series of consistent, FDA accepted neuro-psychological test tools that analyzed a vast range of mind, mood, IQ and memory functions.
The study was completed by 74 healthy volunteers, who were mentally fit, males and females between 22 to 66 years of age. There were 43 in the combination nutraceutical formula (Procera AVH) group and 31 in the placebo group. The average age was 48 years.
The study results showed that Procera AVH outperformed the placebo during the 30 days of the trial.
Procera AVH was superior at improving working memory accuracy, long term memory consolidation and mood. All of these improvements demonstrate that Procera AVH can enhance cognitive processes.
The cognitive processes evaluated tested both primary stages of handling information in conscious awareness in addition to the encoding and recovery of lately learned material. The results showed that improvements in the rate of memory recovery make the participants perform at the level of adults 10 or more years younger.
No side effects or negative reactions was observed during the study.
Vinpocetine is a semi-synthetic alkaloid compound that is derived from vincamine, a natural alkaloid extracted from the periwinkle plant.
Vinpocetine is known to enhance cerebral vascular blood flow, in so doing, making it easy for nutrients, oxygen, vitamins and neurotransmitter substrates to flow into the brain.
Furthermore, vinpocetine improves aspects of brain functioning such as concentration and memory by increase metabolism and energy production in brain cells. Lastly, it acts as antioxidants and also has neuroprotective effect which protects the cells of the brain against stress, toxins and age-related cognitive decline.
Vinpocetine is particularly believed to improve the brain processing speed. It is currently investigated as drug candidate for treating neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases.
Huperzine A is an alkaloid extracted from Huperzia serrate, a firmoss plant.
It is an inhibitor of the enzyme, acetylcholinesterase. This enzyme breaks down acetylcholine in the synaptic junctions between nerves. Therefore, it reduces the activity and level of acetylcholine in the brain.
Huperzine A acts by blocking this the enzyme and in this way, it increases the activity of acetylcholine. Since acetylcholine is the most important neurotransmitter for memory and cognition, huperzine A enhances the alertness, memory, mental focus and other aspects of cognition.
In addition, huperzine A protects brain cells from free radicals. It is also binds to NMDA receptors in the brain to block the release of glutamate which can damage the nerves responsible for signal transmission in the central nervous system.
Several clinical trials now support the use of huperzine A as a brain tonic. Researchers have demonstrated that this alkaloid can improve the memory and cognitive performance of students and patients with Alzheimer’s disease.
Acetyl-l-carnitine is an acetylated metabolite of L-carnitine. It drives energy production in cells by increasing the utilization of fatty acids as energy source. It works by moving fatty acids from the aqueous part of the cytoplasm to the cell’s power center, the mitochondria. This process ensures the breakdown of fats for the needed energy of our body.
This form of carnitine is naturally occurring in our brain and in other parts of the body. It is also present in minimal amounts in our diet and is active in the cellular level and helps in
Acetyl-l-carnitine is preferred as supplement to L-carnitine because it is better absorbed from the intestine. In addition, acetyl-L-carnitine is taken up by cells more efficiently than L-carnitine. In the blood, it is broken down to L-carnitine and acetyl-CoA.
Part of the superiority of acetyl-l-carnitine (over L-carnitine) with regards to bioavailability is the ease with which it crosses the blood-brain barrier.
Once in the brain, this supplement does more than increase energy production in brain cells, it serves as an antioxidant and a neuroprotective agent by preventing the degeneration of brain cells.
The published feedback from most users of Procera AVH was positive. Not only did they attest to its efficacy, they also believed it is one of the only trusted and safe supplements to improve mental performance.
Users report increased awareness, attentiveness and improvements in memory. Additional benefits reported with supplementation with Procera AVH include maintaining better social interaction, improvements in mental capacity and creativity, and enhanced mood.
However, there is a widespread discontent among reviewers regarding the study published on Procera AVH product page.
For one, there is no indication that the study was really published in the journal claimed by the manufactured. A search of such study on PubMed (the central repository for articles published in reputable science journals) found no such mentions.
Even an examination of the study design published on the product page shows glaring failings in methodology. These shortcomings of the study design include small sample size, high dropout rates and lack of peer review by independent researchers.
For all these reasons, it is impossible to even consider the results of the study done on Procera AVH.
However, there are even more faults with the product and its manufacturer. First, the product website hosts a short infomercial to advertise the merits of Procera AVH. The site claims the woman interviewing the company representative is an award-winning investigative reporter when she is really the wife of another representative of the company.
In addition, the product inventor who was advertised as an expert was discovered to have no college degrees or reputation in the worlds of conventional and alternative medicines.
Lastly, there is the damning class action suit brought against Brain Research Labs for claiming that Procera AVH improves brain function. The product manufacturer agreed to a settlement ($20 in cash or 50% off as saving vouchers for those who bought Procera AVH already) to avoid further litigation.
All the signs point to the fact that Procera AVH use false advertising and unfounded research data to sell a product that does not work as described.
Is Procera AVH effective as a brain tonic? No.
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Cyntol is an all natural memory remedy. By supporting key nutrients essential to brain function, Cyntol can help improve memory and learning.