Our Products
About Us
Contact Us
Hello Sign In
Your Account
View My

Anatrin Interactions

Medications That May Interact with Anatrin.
Pin it

Anatrin Interactions

 Serving Size: 3 Capsules
 Servings Per Container:  30


Per Serving

Daily Value

  Magnesium (as Magnesium Oxide)

400 mg


  Ascorbigen Powder

100 mg


     Broccoli Powder (Brassica oleracea) (flower)

400 mg


   Rhodiola Rosea Extract  (Rhodiola Rosea) (root)

100 mg


  Ginger Root Extract (Zingiber officinale) (root)

300 mg


   5-HTP (5-Hydroxytryptophan)

50 mg


   Melatonin Powder

1 mg


     Malic Acid

600 mg


  Other Ingredients: Gelatin, Rice Powder, Magnesium Stearate.
  *Daily Value Not Established

Daily Dosage: As a dietary supplement, take two capsules in the morning and one capsule in the evening with 8 ounces of water. 45-60 days of continuous use is necessary for optimum results.

Anatrin Research:

Possible Interactions with:Magnesium (as Magnesium Oxide)
Also listed as: Magnesium

If you are currently being treated with any of the following medications, you should not use magnesium without first talking to your healthcare provider.

Antibiotics - The absorption of quinolone antibiotics (such as ciprofloxacin and moxofloxacin), tetracycline antibiotics (including tetracycline, doxycycline, and minocycline), and nitrofurantoin is diminished when taken with magnesium supplements. Therefore, magnesium should be taken two to four hours before or after taking these medications to avoid interference with absorption.

Blood Pressure Medications, Calcium Channel Blockers - Magnesium may increase the likelihood of negative side effects (such as dizziness, nausea, and fluid retention) from calcium channel blockers (particularly nifedipine) in pregnant women. Other calcium channel blockers include amlodipine, diltiazem, felodipine, and verapamil. 

Diabetic Medications - Magnesium hydroxide, commonly found in antacids, may increase the absorption of glipizide and glyburide, medications used to control blood sugar levels. Ultimately, this may prove to allow for reduction in the dosage of those medications.

Digoxin - It is important that normal levels of magnesium be maintained while taking digoxin because low blood levels of magnesium can increase adverse effects from this drug. In addition, digoxin can lead to increased loss of magnesium in the urine. A healthcare provider will follow magnesium levels closely to determine whether magnesium supplementation is necessary.

Diuretics - Two types of diuretics known as loop (such as furosemide) and thiazide (including hydrochlorothiazide) can deplete magnesium levels. For this reason, physicians who prescribe diuretics may consider recommending magnesium supplements as well.

Hormone Replacement Therapy for menopause - Magnesium levels tend to decrease during menopause. Studies suggest, however, that hormone replacement therapy may help prevent the loss of this mineral. Postmenopausal women or those taking hormone replacement therapy should talk with a healthcare provider about the risks and benefits of magnesium supplementation.

Levothyroxine - There have been case reports of magnesium containing antacids reducing the effectiveness of levothyroxine, which is taken for an under active thyroid. This is important because many people take laxatives containing magnesium without letting their doctor know.

Penicillamine - Penicillamine, a medication used for the treatment of Wilson's disease (a condition characterized by high levels of copper in the body) and rheumatoid arthritis, can inactivate magnesium, particularly when high doses of the drug are used over a long period of time. Even with this relative inactivation, however, supplementation with magnesium and other nutrients by those taking penicillamine may reduce side effects associated with this medication. A healthcare practitioner can determine whether magnesium supplements are safe and appropriate if you are taking penicillamine.

Tiludronate and Alendronate - Magnesium may interfere with absorption of tiludronate, a medication similar to alendronate that is used for the treatment of osteoporosis. This interaction has not been reported with alendronate specifically. Magnesium supplements or magnesium-containing antacids should be taken at least two hours before or two hours after taking these medications to minimize potential interference with absorption.

Others - Aminoglycoside antibiotics (such as gentamicin and tobramycin), thiazide diuretics (such as hydrochlorothiazide), loop diuretics (such as furosemide and bumetanide), amphotericin B, corticosteroids, antacids, and insulin may lower magnesium levels. Please refer to the depletions monographs on some of these medications for more information.


Possible Interactions with: Ascorbigen Powder

We are unaware of any interactions with this supplement.

Possible Interactions with: Broccoli Powder (Brassica oleracea) (flower)

We are unaware of any interactions with this supplement.

Possible Interactions with: Rhodiola Rosea Extract(Rhodiola Rosea)(root)

We are unaware of any interactions with this supplement.

Possible Interactions with: Ginger Root Extract (Zingiber officinale) (root)
Also listed as: Ginger; Zingiber officinale

If you are currently being treated with any of the following medications, you should not use ginger without first talking to your healthcare provider.

Blood-thinning medications - Although ginger may interfere with blood clotting, there have been no scientific or case reports of interactions between ginger and blood-thinning medications. However, people taking these medications with ginger should be monitored closely by a healthcare practitioner for risk of bleeding.

Cyclophosphamide - Ginger may reduce the toxic side effects of cyclophosphamide (a medication used to treat a variety of cancers). More research is needed in this area.

Possible Interactions with: 5-HTP (5-Hydroxytryptophan)
Also listed as: 5-HTP; 5-Hydroxytryptophan (5-HTP)

If you are currently being treated with any of the following medications, you should not use 5-HTP without first talking to your healthcare provider.

Antidepressant Medications

Individuals taking the antidepressant medications known as selective serotonin reuptake inhibitors (SSRIs) (such as fluoxetine, paroxetine, sertraline, and citalopram) and monoamine oxidase inhibitors (MAOIs) (such as phenelzine, isocarboxazid, selegiline, and tranylcypromine) should not use 5-HTP as these medications enhance the action of these drugs and may increase the risk for developing a dangerous condition known as "serotonin syndrome." Serotonin syndrome is characterized by mental status changes, rigidity, hot flashes, rapidly fluctuating blood pressure and heart rate, and possibly coma. Similarly, other drugs for depression that interfere with the uptake of the neurotransmitter serotonin, namely trazodone and venlafexine, may also lead to serotonin syndrome when used along with 5-HTP.


Taking 5-HTP with carbidopa, a medication used to treat Parkinson's disease, has been associated with side effects including scleroderma-like illnesses (a condition in which the skin becomes hard, thick, and inflamed).

Sumatriptan - Similar to antidepressants, sumatriptan, a medication used for migraine headaches that works by stimulating serotonin receptors in the brain, should also not be used in combination with 5-HTP because of the risk for serotonin syndrome.


Tramadol, used for pain control, may also increase serotonin levels too much if taken in combination with 5-HTP. Serotoninsyndrome has been reported in some people taking the two together.


Use of zolpidem, a medication for insomnia, can cause hallucinations when used with SSRI antidepressants. Because 5-HTP may work similarly to SSRIs, the combination of 5-HTP with zolpidem could, theoretically, lead to hallucinations as well.

Possible Interactions with:  Melatonin Powder
Also listed as: Melatonin

If you are currently being treated with any of the following medications, you should not use melatonin without first talking to your healthcare provider.

Antidepressant Medications - In an animal study, melatonin supplements reduced the antidepressant effects of desipramine and fluoxetine. More research is needed to determine whether these effects would occur in people. In addition, fluoxetine (a member of a class of drugs called selective serotonin reuptake inhibitors or SSRIs) has led to measurable depletion of melatonin in people.

Antipsychotic Medications - A common side effect of antipsychotic medications used to treat schizophrenia is a condition called tardive dyskinesia, a movement disorder of the mouth characterized by a constant chewing motion and darting action of the tongue. In a study of 22 people with schizophrenia and tardive dyskinesia caused by antipsychotic medications, those who took melatonin supplements had significantly reduced mouth movements compared to those who did not take the supplements.

Benzodiazepines - The combination of melatonin and triazolam (a benzodiazepine medication used for the treatment of anxiety and sleep disorders) improved sleep quality in one study. In addition, there have been a few reports suggesting that melatonin supplements may help individuals stop using long-term benzodiazepine therapy. (Benzodiazepines are highly addictive.)

Blood Pressure Medications - Melatonin may reduce the effectiveness of blood pressure medications like methoxamine and clonidine. In addition, medications in a class called calcium channel blockers (such as nifedipine, verapamil, diltiazem, amlodipine, nimodipine, felodipine, nisoldipine, and bepridil) may decrease melatonin levels.

Use of beta-blockers (another class of high blood pressure medications including propranolol, acebutolol, atenolol, labetolol, metoprolol, pindolol, nadolol, sotalol, and timolol) may reduce melatonin production in the body.

Blood-thinning Medications, Anticoagulants - Melatonin may increase the risk of bleeding from anticoagulant medications such as warfarin.

Interleukin-2 - In one study of 80 cancer patients, use of melatonin in conjunction with interleukin-2 led to more tumor regression and better survival rates than treatment with interleukin-2 alone.

Nonsteroidal Anti-inflammatory Drugs (NSAIDs) - NSAIDs such as ibuprofen may reduce the levels of melatonin in the blood.

Steroids and Immunosuppressant Medications - Melatonin should not be taken with corticosteroids or other medications used to suppress the immune system because the supplement may cause them to be ineffective.

Tamoxifen - Preliminary research suggests that the combination of tamoxifen (a chemotherapy drug) and melatonin may benefit certain patients with breast and other cancers. More research is needed to confirm these results.

Other Substances - Caffeine, tobacco, and alcohol can all diminish levels of melatonin in the body while cocaine and amphetamines may increase melatonin production.

Possible Interactions with: Malic Acid
lso listed as: fruit acid or apple acid

Malic acid should be avoided in women who are pregnant or nursing due to the lack of information regarding safety in these populations.



If you are experiencing the discomforts of pain and tenderness, Anatrin is a fibromyalgia remedy designed to provide energy while also helping to reduce pain and fatigue.