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"All of the products on progressivehealth.com are formulated with quality in mind. Our team of naturopathic physicians closely analyzed each formula to find the best balance of effective ingredients. I personally take Advecia for hair maintenance, Acktiva coral calcium for long term health, and Balance Point Multivitamin to help fulfill my daily nutritional needs."
Brad Chase, President
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Lipitrex Supplement Facts
Daily Dosage: As a dietary supplement, take two capsules in the morning and two capsules in the afternoon with 8 ounces of water. 45-60 days of continuous use is necessary for optimum results.
Lipitrex Research: Magnesium- Magnesium is increasingly studied in relation to obesity and insulin resistance.
In fact a recent study showed that deficiency of magnesium is related to insulin resistance as early as childhood and suggested supplementation as an important tool in reducing diabetes in obese children (12). As well, low levels of magnesium prevalent in overweight and obese individuals may be an independent risk factor for cardiovascular disease (13, 14).
Chromium- This required mineral is lacking in many diets and is vital to glucose metabolism as it is a cofactor for glucose tolerance factor. Chromium supplementation has been associated with an increase in lean body mass, a decrease in percentage body fat, and an increase in the basal metabolic rate (8-10).
The results of a randomized double blind placebo controlled study of chromium supplementation suggest a relatively small reduction in body weight when compared with placebo during an intervention period of 6–14 weeks in patients with an average BMI of 28–33 (11). The meta-analysis of trials reported an absence of adverse effects.
Green Tea Extract- Green tea has recently been recognized for its ability to increase the metabolism of fat and decrease weight.
Green tea is thermogenic in nature; increasing the oxidation of fat molecules in the body. It may prove helpful in persons suffering from obesity and are trying to lose weight.
Coleus Forskohlii- Progressive Health's recently updated Lipitrex formulation includes the Indian plant, Coleus Forskohlii. Coleus forskohlii roots, the only known plant source of forskolin, is a natural compound that has been shown to increase lean body mass and helps optimize body composition through cAMP activation.
Raised intracellular cAMP levels have shown to decrease fat deposition and promote other significant physiological and biochemical effects, including:
A study published in the December 2005 Journal of the International Society of Sports Nutrition entitled "Effects of Coleus forskohlii extract supplementation on body composition and markers of health in sedentary overweight females" indicated that a Coleus forskohlii extract promotes favorable changes in body composition. Additionally, no clinically significant interactions were seen in metabolic markers, blood lipids, muscle and liver enzymes, electrolytes, red cells, white cells, hormones (insulin, TSH, T3, T4), heart rate or blood pressure. Pinnothin- Derived from the seeds of the Korean Pine Nut tree Pinus koraenisis, this product (which just became widely available in 2005) contains pinolenic acid which helps suppress appetite by stimulating the appetite controlling hormone cholecystokinin (7).
CLA- A clinical study recently concluded, “this study shows that CLA supplementation for 24 mo in healthy, overweight adults was well tolerated. It confirms also that CLA decreases BFM in overweight humans, and may help maintain initial reductions in BFM and weight in the long term (17)”. As well, CLA can reduce all parameters of appetite - hunger, satiety and fullness (18).
Citrus Aurantium Extract- Bitter orange is the common name for this medicinal plant which has an impressive body of research building for its use in weight reduction. A recent study demonstrated that administration of an extract of this plant results in increased thermic response to meals in women and does not cause increases in blood pressure or heart rate (15).
A review of clinical studies concluded that citrus aurantium products “may be the best thermogenic substitute for ephedra”, causing an increased metabolic rate (16).
Guarana Extract- This supplement is derived from the seeds of Paullinia cupana. An herbal preparation from South America containing guarana extract demonstrated the ability to significantly delayed gastric emptying, reduced the time to perceived gastric fullness and induced significant weight loss over 45 days in a double-blind placebo-controlled parallel trial (19).
Another randomized double blind trial examining the effect of a combination of Ma Huang and Guarana showed significant short term fat and weight loss (20).
Caffeine- Caffeine has long been used for weight loss due to its demonstrable thermogenic effects. A study published this year concluded that high caffeine intake was associated with weight loss through thermogenesis and fat oxidation and with suppressed leptin in women (21).
Another randomized double-blind placebo-controlled clinical trial of a product containing ephedrine and caffeine showed that subjects taking the treatment experienced greater weight loss, without an increase in blood pressure, pulse, or the rate of adverse events, and in the absence of any lifestyle treatment to change dietary or exercise behavior (22).
Lipitrex References: 1. Takii H et al. Antidiabetic effect of glycyrrhizin in genetically diabetic KK-Ay mice. Biol Pharm Bull. 2001 May;24(5):484-7. 2. Nakagawa K et al. Licorice flavonoids suppress abdominal fat accumulation and increase in blood glucose level in obese diabetic KK-A(y) mice. Biol Pharm Bull. 2004 Nov;27(11):1775-8. 3. Naruto E and Buko V. Hypolipidemic effect of pantothenic acid derivatives in mice with hypothalamic obesity induced by aurothioglucose. Exp Toxicol Pathol. 2001 Oct;53(5):393-8. 4. Bays H and Stein EA. Pharmacotherapy for dyslipidaemia--current therapies and future agents. Expert Opin Pharmacother. 2003 Nov;4(11):1901-38. 1. 5. Henning BF et al. Vitamin supplementation during weight reduction--favourable effect on homocysteine metabolism. Res Exp Med (Berl). 1998 Jul;198(1):37-42. 6. Ortega Rm et al. Difference in the breakfast habits of overweight/obese and normal weight schoolchildren. Int J Vitam Nutr Res. 1998;68(2):125-32. 7. Food Ingredient News, BCC Inc. Norwalk, CT 2005;13(6):12 8. Crawford V, Scheckenbach R, Preuss HG. Effects of niacin-bound chromium supplementation on body composition in overweight African-American women. Diabet Obes Metab1999;1:331–7. 9. Anderson RA. Effects of chromium on body composition and weight loss. Nutr Rev1998;56:266–70. 10. Anderson RA. Essentiality of chromium in humans. Sci Total Environ1989;86:75–81 11. Chromium picolinate for body weight reduction. Meta-analysis of randomized trials. Int J Obes Relat Metab Disord2003;27:522–9 12. Huerta MG et al. Magnesium deficiency is associated with insulin resistance in obese children. Diabetes Care. 2005 May;28(5):1175-81. 13. Laires MJ et al. Magnesium, insulin resistance and body composition in healthy postmenopausal women. J Am Coll Nutr. 2004 Oct;23(5):510S-513S. 14. Lelovics Z. Relation between calcium and magnesium intake and obesity. Asia Pac J Clin Nutr. 2004;13(Suppl):S144. 15. Gougeon R et al. Increase in the thermic effect of food in women by adrenergic amines extracted from citrus aurantium. Obes Res. 2005 Jul;13(7):1187-94. 16. Preuss HG et al. Citrus aurantium as a thermogenic, weight-reduction replacement for ephedra: an overview. J Med. 2002;33(1-4):247-64. 17. Gaullier JM et al. Supplementation with conjugated linoleic acid for 24 months is well tolerated by 1an reduces body fat mass in healthy, overweight humans. J Nutr. 2005 Apr;135(4):778-84. 18. Kamphuis MM et al. Effect of conjugated linoleic acid supplementation after weight loss on appetite and food intake in overweight subjects. Eur J Clin Nutr. 2003 Oct;57(10):1268-74. 19. Andersen T and Fogh J. Weight loss and delayed gastric emptying following a South American herbal preparation in overweight patients. J Hum Nutr Diet. 2001 Jun;14(3):243-50. 20. Boozer CN et al. An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial. Int J Obes Relat Metab Disord. 2001 Mar;25(3):316-24. 21. Westerterp-Plantenga Ms et al. Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation. Obes Res. 2005 Jul;13(7):1195-204.
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