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Herdox Supplement Facts
Learn more about the ingredients in Herdox.
Daily Dosage: As a dietary supplement, take two capsules in the morning and one capsule in the afternoon with 8 ounces of water. 45-60 days of continuous use is necessary for optimum results.
Vitamin A- Vitamin A is a potent immune stimulatory vitamin. Studies have shown that patients with vitamin A deficiency experience more shedding of the herpes simplex virus (1). As well, isomers of retinoic acid ( a form of vitamin A) have demonstrated the ability to inhibit HSV replication (2).
Vitamin E- Vitamin E is often given with vitamin A to improve the clinical response and reduce possible toxicity associated with high doses of vitamin A. A patented combination of antioxidants containing vitamin E has shown clinical effectiveness in reducing lesion development, duration and severity scores significantly compared to vehicle control or acyclovir (a prescription anti-viral) (3). Studies conducted by dentists have demonstrated vitamin E alone is effective for ulcerative herpetic lesions (4, 5).
Zinc- One of the most important minerals for immune function, zinc has been widely studied for prevention and treatment of infections. A clinical trial showed that systemic zinc sulphate supplementation given a t a dose of 45mg daily during February, March, September and October appeared to reduce both the number of episodes and the time to recovery of herpes labialis over a 12 month period (6). Topical treatment with zinc solutions have also been effective in herpes simplex infections (7, 8).
Selenium- The mineral selenium is also required for basic immune function. The role of selenium in anti-viral medicine is becoming quite clear, as numerous pharmaceutical anti-viral drugs are in the process of creation. A newly designed class of drugs containing selenium exhibit strong inhibition of cythopatic activity of HSV-1 (9).
L-lysine- Classically known as an anti-herpes nutrient, patients suffering from this infection are well aware of the impact of lysine supplementation. Lysine is an effective preventative therapy, as well as a treatment option (10, 11). A clinical trial of an ointment containing lysine, zinc and botanicals revealed full resolution of symptoms in 40% of patients with oral herpes by the third day of treatment and 87% by the sixth day (12).
Monolaurin- Monolaurin is a naturally derived supplement made from lauric acid (a fatty acid in breast milk and coconut milk) and glycerin. It is recommended for viral infections like Epstein-Barr, influenza, measles and herpes as a result of in vitro studies demonstrating anti-viral activity against these and numerous other viruses (13).
Lactoferrin- Lactoferrin is a glycoprotein with many activities. It is an important factor in immune regulation and defense mechanisms against bacteria, fungi, and viruses. Lactoferrin has demonstrated anti-viral activity against HSV-1 and HSV-2 and exhibits synergistic activity with acyclovir against these same viruses (14).
Garlic Powder- Garlic is often described as the panacea of botanical medicine. This common culinary herb exhibits anti-viral activity against many viruses including HSV-1 and HSV-2 (15).
Lemon Balm Powder- Melissa officinalis is widely known in Germany for its potent anti-viral activity and is recommended for many infections, including influenza and herpes. This herb contains numerous components that inhibit replication of HSV-1 and HSV-2 (16, 17). Many topical preparations contain lemon balm which is an effective treatment for recurring herpes labialis and can reduce frequency of subsequent outbreaks (18).
Olive Leaf Extract- Olea europea is a relatively new recommended herb for conditions of an infectious nature. It has demonstrated anti-viral activity against HIV and viral haemorrhagic septicaemia virus (19, 20). Researchers believe olive leaf may be a promising source of natural anti-viral compounds.
Propolis Extract- Propolis is a naturally occurring product derived from beehives which contains a large flavonoid component. It displays anti-HSV-1 activity both in vitro and in vivo (21). Propolis may prevent the virus from adhering to host cells and also prevent replication of the virus. In a multi-center study, a preparation of propolis demonstrated superior activity over both acyclovir and placebo ointments in healing genital herpetic lesions, and in reducing local symptoms (22).
1. Mostad SB et al. Cervical shedding of herpes simplex virus in human immunodeficiency virus-infected women: effects of hormonal contraception, pregnancy, and vitamin A deficiency. J Infect Dis. 2000 Jan;181(1):58-63.
2. Issacs CE et al. Inhibition of herpes simplex virus replication by retinoic acid.
3. Sheridan J et al. Evaluation of antioxidant healing formulations in topical therapy of experimental cutaneous and genital herpes simplex virus infections. Antiviral Res. 1997 Dec;36(3):157-66.
4. Nead DE. Effective vitamin E treatment for ulcerative herpetic lesions.
5. Fink M and Fink J. Treatment of herpes simplex by alpha-tocopherol (vitamin E). Br Dent J 1980;148:246.
6. Femiano F, Gombos F and Scully C. Recurrent herpes labialis: a pilot study of the efficacy of zinc therapy.J Oral Pathol Med. 2005 Aug;34(7):423-5.
8. Tennican P et al. Topical zinc in the treatment of mice infected intravaginally with herpes genitalis virus. Proc Soc Exp Biol Med 1980;164:593.
9. Wojtowicz H et al. Azaanalogues of ebselen as antimicrobial and antiviral agents: synthesis and properties.Farmaco. 2004 Nov;59(11):863-8.
10. Milman N and Scheibel J. Lysien prophylaxis in recurrent herpes simplex labilais: a double blind crossover study. Acta Derm Venereol 1980;60:85.
11. Kagan C. Lysine therapy for herpes simplex. Lancet 1974;1:137.
12. Singh BB et al. Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes.Altern Med Rev. 2005 Jun;10(2):123-7.
13. Hierholzer JC and Kabara JJ. In vitro effects of Monolaurin compounds on enveloped RNA and DNA viruses. J. Food Safety 4:1, 1982.
14. Andersen JH, Jenssen H and Gutteberg TJ. Lactoferrin and lactoferricin inhibit Herpes simplex 1 and 2 infection and exhibit synergy when combined with acyclovir. Antiviral Res. 2003 May;58(3):209-15.
15. Weber ND et al. In vitro virucidal effects of Allium sativum (garlic) extract and compounds. Planta Med. 1992 Oct;58(5):417-23.
16. Allahverdiyev A et al. Antiviral activity of the volatile oils of Melissa officinalis L. against Herpes simplex virus type-2.Phytomedicine. 2004 Nov;11(7-8):657-61.
17. Dimitrova Z et al. Antiherpes effect of Melissa officinalis L. extracts. Acta Microbiol Bulg. 1993;29:65-72.
18. Koytchev R, Alken Rg and Dundarov S. Balm mint extract (Lo-701) for topical treatment of recurring herpes labialis. Phytomedicine. 1999 Oct;6(4):225-30.
19. Lee-huang S et al. Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment. Biochem Biophys Res Commun. 2003 Aug 8;307(4):1029-37
20. Micol V et al. The olive leaf extract exhibits antiviral activity against viral haemorrhagic septicaemia rhabdovirus (VHSV). Antiviral Res. 2005 Jun;66(2-3):129-36. Epub 2005 Apr 18.
21. Huleihel M and Isanu V. Anti-herpes simplex virus effect of an aqueous extract of propolis. Isr Med Assoc J. 2002 Nov;4(11 Suppl):923-7.
22. Vynograd N, Vynograd I and Sosnowski Z. A comparative multi-centre study of the efficacy of propolis, acyclovir and placebo in the treatment of genital herpes (HSV). Phytomedicine. 2000 Mar;7(1):1-6.
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Herdox is a natural approach to herpes management that helps limit the number and severity of breakouts.