Listol Supplement Facts

Dosage and Directions: As a dietary supplement, adults and children over the age 12, take 3 capsules twice daily immediately following a meal. Children under 12 take 3 capsules once daily immediately following a meal.

Listol Research:

Vitamin B6. Pyridoxine is essential for proper function of the nervous system, so it comes as no surprise that this vitamin can reduce central nervous system excitability in children.

Researchers conducted a clinical study where 52 hyperexcitable children were given a regimen of vitamin B6 and magnesium for 3-24 weeks. The results showed that in all patients, symptoms of hyperexcitability (physical aggressivity, instability, scholar attention, hypertony, spasm, myoclony) were reduced after 1 to 6 months treatment (1)
 

Iron. Research indicates that iron deficiency is associated with attention-deficit/hyperactivity disorder in children.

Markers of iron status are significantly lower in children with ADHD than healthy controls (2). As well, lower serum values of ferritin are directly correlated with severity of symptoms and cognitive deficits. Treatment with iron in children with ADHD has shown improvements in the Conners Rating Scale for Parents (3). Learn more about iron and ADHD.
 

Magnesium. In a study of 116 children with ADHD magnesium deficiency was observed in 95% of the subjects. Analysis of the data showed a correlation between levels of magnesium and the quotient of development to freedom from distractibility (4).

A Supplementation with magnesium for 6 months in children who have ADHD and magnesium deficiency has demonstrated decreased hyperactivity in a controlled trial (5). Decreased hyperexcitabilty has also been established with magnesium and vitamin B6 supplementation (1).
 

Zinc. Another essential mineral, zinc has also been linked to ADHD.

A study conducted to explore the relationship of zinc nutrition to the severity of attention-deficit/hyperactivity disorder (ADHD) symptoms in a middle-class American sample with well-diagnosed ADHD showed that serum zinc levels correlated at with parent-teacher-rated inattention (6).

A double blind randomized placebo controlled trial of supplementation with zinc plus methylphenidate (pharmaceutical treatment) for 6 weeks in children with ADHD concluded that Parent and Teacher Rating Scale scores improved when compared to placebo plus methylphenidate (7).

Another double blind randomized placebo controlled trial of supplementation with zinc sulfate alone demonstrated zinc was superior to placebo in reducing symptoms of hyperactivity, impulsivity and impaired socialization in patients with ADHD, and was well tolerated (8). More information about ADHD and Zinc.
 

Copper. When supplementing with zinc it is always important to take additional copper to prevent deficiency of this trace mineral, as zinc and copper compete for absorption.

Furthermore, copper levels are observed to be lower in children with hyperactivity (9).
 

Phosphatidylserine. An essential phospholipid, phosphatidylserine can ameliorate symptoms of ADHD. An in-office trial of phosphatidylserine supplementation for up to 4 months showed benefit in 90% of cases of ADHD treated in a physician’s office, most notably with learning and attention improvements (10, 11). Learn more about phosphatidylserine and adhd.
 

Di-Methyl Glycine. Abnormal glucose metabolism is a proposed contributor to ADHD and treatment with dimethyl glycine may improve symptoms of hypoglycemia, which can occur in some patients with ADHD.
 

Glycine. Glycine is a basic amino acid which is vital for proper nervous system function. Glycine supplementation in animals has been shown to reduce hyperactivity through dopaminergic pathwaws (12,13). In one case study, oral treatment with glycine improved hyperactivity in a young boy (14).
 

GABA Powder. GABA pathways in the brain appear to play a role in certain cognitive disorders like ADHD. Researchers have proposed using pharmaceutical GABA enhancers to treat conditions including ADHD (15). Learn more about ADHD and GABA.
 

DMAE Bitartatrate. DMAE is a precursor for phosphatidylcholine, an important phospholipid in the brain. Supplementation with DMAE has demonstrated improvements in hyperkinesis, an older term for ADHD (16). Learn more about DMAE and GABA. Learn more about ADHD and DMAE.
 

Huperzine A Extract. This natural compound is drawing much attention for its effects on cognitive function, enhancing memory and treating cognitive deficits (17,18). A double blind placebo controlled trial of huperzine A supplementation in patients with cognitive deficits of Alzheimer’s type showed it is a safe and effective medicine, improving cognition, behavior, activities of daily living and mood (19).