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Prosta Metto

Prosta-Metto is an oral formulation of natural supplements for improving prostate health and urinary difficulties in men. Even though the manufacturer advertises that the supplement is not intended for treating prostate diseases, the ingredients included are good enough to be help treat prostate enlargement. Read on to find out what these ingredients are, what scientific studies say about their effects on the prostate and how they help support the organ.
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What is Prosta Metto?

Prosta Metto is an oral, natural supplement formulated from a proprietary blend of herbs and minerals including the popular herb, saw palmetto. In fact, Prosta Metto derives its name from this prostate-supporting herb.

This herbal supplement is manufactured by Vitamin World and marketed to support prostate and urinary health in men. However, Prosta Metto carries a warning on its label stating that the herbal product is not intended for the treatment or prevention of any disease.

While saw palmetto is the primary active ingredient in this prostate supplement, other ingredients also contribute to its therapeutic effect on the prostate and urinary tract.

The active ingredients of Prosta Metto act on the prostate and urinary tract to provide anti-inflammatory, antioxidant, and antibacterial actions.

In addition, some of its active ingredients also possess androgenic hormone-inhibiting properties known to improve prostate health in men. This is perhaps the most beneficial and important effect of Prosta Metto’s active ingredients on the prostate.

For dosage directions, it is recommended to take 2 soft gels of the supplement daily along with a meal. A bottle of Prosta Metto contains 240 soft gels, enough for 120 days of supplementation.

Prosta Metto: Side Effects

Prosta Metto is formulated from natural ingredients that have been proven to be safe and well tolerated. However, it is not completely free of side effects.

Almost all cases of side effects reported from the use of Prosta Metto are mild and are actually preventable in some way.

Common complaints from users include gastro-intestinal discomforts and nausea. To prevent gastro-intestinal side effects, users should not take the supplement on an empty stomach.

For users who experience nausea after taking the herbal product, this adverse effect is expected to resolve gradually with time as the body develops tolerance to the supplement.

Although rare, other minor complaints may include dizziness, headache, irritability, insomnia, and vomiting.

Prosta Metto: Contraindications

Since some of the active ingredients of Prosta Metto are known to interact with certain medications, the supplement itself is also expected to interact with such medications.

For example, saw palmetto can disrupt the process of blood clot formation in the body. Therefore, taking blood thinning medications or anticoagulants along with this supplement may increase the risk of internal bleeding.

In addition, pygeum (another ingredient of Prosta Metto) and saw palmetto interact with sex hormones and hormonal drugs especially those containing testosterone and estrogen. Therefore, these herbs can reduce the effectiveness of oral contraceptives.

Because the active ingredients of Prosta Metto respectively interact with different medications, users should generally avoid combining Prosta Metto with the groups of medications listed in the table below.

Drugs Not To Be Taken With Prosta Metto
  • Diuretics
  • Lithium
  • NSAIDs
  • Medications for high blood pressure
  • Oral contraceptives
  • Medications for diabetes
  • Anticoagulants and Blood thinners (aspirin, warfarin)

Prosta Metto can theoretically increase the risk of heart diseases in men who have histories of heart attack. This is due to the actions of beta-sitosterol found in saw palmetto.

Furthermore, to prevent liver problems, Prosta Metto should not be taken for a long period of time because an ingredient of the product, uva-ursi, contains hydroquinine.

People who are allergic to pumpkin seed, an active ingredient of Prosta Metto, should not use the supplement to avoid fatal allergic reactions. Any allergic reaction, regardless of its severity, should be treated as a medical emergency to prevent fatal complications.

Lastly, Prosta Metto is indicated for use by men aged 18 and above only. The instructions on the label of the product specifically state that women and children below the age of 18 should not use the supplement.

Active ingredients of Prosta Metto

Saw Palmetto (Serenoa repens)

Saw palmetto is the primary active ingredient of Prosta Metto.

Although the fruits (also known as berries) of saw palmetto have been traditionally used as a food source by Native Americans, its health benefits make it a popular herb in traditional medicine.

Saw palmetto fruit contains bioactive phytochemicals such as phytosterols and fatty acids. These compounds have been identified in multiple studies to be responsible for most of its therapeutic actions. Therefore, extracts made from saw palmetto fruits are standardized by these chemicals.

The active ingredients of saw palmetto target the action of androgens (especially DHT or dihydrotestosterone) on the prostate in a number of ways.

First, saw palmetto inhibits the enzymes, 5-alpha reductase type 1 and 2, responsible for converting testosterone to DHT. This decreases the activities of DHT in the prostate and effectively reduces prostate enlargement.

Secondly, saw palmetto prevents DHT from binding to androgenic receptors. For DHT to be activated in the prostate, it must bind to these receptors. This antagonism thereby hinders DHT from acting on the prostate.

However, the effects of saw palmetto on the prostate are not limited to the androgens. It also contracts the smooth muscles of the urethral sphincter in the prostate.

This action eases the pressure in the prostatic urethra thereby improving urinary functions.

The result of a study published in The Journal of Urology in 2000 established the efficacy of saw palmetto in improving prostate health. In this study, 160 mg of saw palmetto fruit extract was found to significantly improve the symptoms of BPH (benign prostatic hyperplasia) in 22 patients compared to another 22 patients who were given placebo and experienced no improvements.

Pygeum

Pygeum is another clinically-proven herb included in Prosta Metto for its therapeutic effects on the prostate. Pygeum is an evergreen tree native to the mountainous region of Sub-Saharan Africa.

For centuries, extracts from the bark of this tree have been used for treating various medical conditions in African traditional medicine.

Pygeum bark extracts contain mainly four groups of chemicals that work in similar ways to saw palmetto. They also target the effects of androgens on the prostate. But unlike saw palmetto, pygeum reduces the level of testosterone (and, by extension, DHT) in the prostate by competing with the precursors of this hormone.

Other ways by which pygeum affects the action of androgens in the prostate include:

  • By reducing the activity of prolactin which is involved in the uptake of testosterone in the prostate
  • By inhibiting androgen production through cholesterol (cholesterol is essential in the biosynthesis of androgens)

The cumulative effect of all these actions makes pygeum an excellent herb for improving prostate and urinary health.

Pumpkin Seed Oil

Pumpkin seed oil is best known for its culinary use. However, it contains some essential fatty acids that have demonstrated considerable therapeutic properties.

The oil is obtained from crushed pumpkin seed and used in a variety of dishes. It is often added to foods after cooking because heat destroys its essential fatty acids.

Specifically, pumpkin seed oil contains beta sitosterol, a compound also found in saw palmetto. This bioactive phytosterol improves prostate health in the same way as the one found in saw palmetto.

In addition, it also contains omega 3 and 6 fatty acids that are capable of fighting inflammation, including prostate inflammation in the body.

A 2009 study published in the journal, Nutrition Research and Practice confirmed that pumpkin seed oil can indeed improve prostate health in men. In this study, a combination of 320 mg per day of saw palmetto and pumpkin seed oil was shown to improve BPH in patients after 6 months.

Uva-Ursi

Uva-ursi (Arctostaphylos uva-ursi) refers to a group of plants commonly known as bearberry.

It is primarily included as an ingredient of Prosta Metto to complement the other active ingredients by improving the urine flow.

While the herb may not be very popular in the US, it is extensively used in Europe. In fact, uva-ursi is approved in Germany for treating inflammation of the lower urinary tract by the country’s regulatory body.

Arbutin, an active chemical found in uva-ursi and a derivative of hydroquinine, is majorly responsible for its therapeutic actions. Importantly, this chemical relieves inflammation and oxidative stress in the urinary tract.

In addition, it prevents and fights infections especially bacterial infections of the urinary tract.

Although there are claims that uva-ursi can improve prostate health, there is no evidence to prove that it directly acts on the prostate. However, its effects on the urinary tract are also likely to indirectly improve the prostate because of the connection between the two.

Vitamin B6 (Pyridoxine hydrochloride)

Vitamin B6 is one of the B vitamins involved in many enzymatic reactions in the body. Together with other B group vitamins, vitamin B6 is required for the synthesis and repair of DNA.

Its role as an ingredient of Prosta Metto is unclear. It is likely that vitamin B6 is included in the supplement to improve general health rather than having a direct effect on the prostate or urinary tract.

However, some studies have been able to link vitamin B6 to prostate cancer in men, although with contrasting results.

For example, the result of a population study published in American Journal of Clinical Nutrition showed that high body levels of vitamin B6 reduced death rate from prostate cancer in 525 prostate cancer patients.

Alternatively, another study published in International Journal of Cancer showed that high levels of vitamin B6 increased the risk of prostate cancer in some men.

Prosta Metto delivers a dose of 10 mg vitamin B6 in one soft gel, making a daily dose of 20 mg from the two recommended servings of the supplement. This dosage recommendation is still far off the high level required to increase the risk of prostate cancer in the study mentioned above.

Zinc

Zinc is an essential trace nutrient that acts as a cofactor in many enzymes. It is needed for various cellular metabolisms in the body and also to improve the immune system.

While the mineral is found in other body organs, the highest concentration is in the prostate. The role of zinc in this organ is not properly understood. However, a few studies have explored the association between the two.

One study published in the Journal of Experimental and Clinical Cancer Research showed that men with low levels of zinc were more at risk of prostate cancer.

Another study published in the International Journal of Antimicrobial Agents showed that zinc salt administered through injection was effective in improving BPH in men.

The zinc content of Prosta Metto is delivered in form of zinc gluconate, a zinc salt with a high absorption rate.

Others

Other ingredients found in Prosta Metto include gelatin, beeswax/soybean oil mixture, glycerin, lecithin, caramel color, and titanium dioxide color.

Although they are also important ingredients, they do not contribute any therapeutic health benefit to prostate and urinary health. These inactive ingredients are primarily used as binders, fillers, stabilizers and general excipients during the production process of the product.

How Effective is Prosta Metto?

Prosta Metto delivers adequate amounts of standardized herbs proven and renowned worldwide for improving both prostate and urinary health.

Although, the supplement itself has not been a subject of any clinical study, its chief ingredient, saw palmetto, is the most clinically studied and popular herb for improving the prostate.

Unlike most other prostate herbal supplements with less potent ingredients, Prosta Metto contains not just more potent ingredients, but a longer list of them. Furthermore, the diverse ingredients of Prosta Metto target a wider range of symptoms and act differently to improve the prostate and urinary tract.

For instance, saw palmetto targets the production of DHT through the inhibition of 5-alpha-reductase while pygeum does this through prolactin and cholesterol.

In addition, saw palmetto acts on the muscles of the urethra sphincter and also targets androgen receptors; pygeum targets precursors of androgens; while uva-ursi flushes the urinary tract.

The anti-inflammatory and anti-oxidant actions of pumpkin seed oil and zinc will also complement all of the actions mentioned above.

In conclusion, Prosta Metto can indeed support prostate and urinary health as well as help treat and prevent prostate and urinary problems. Furthermore, past users confirm that this supplement works. In fact, Prosta Metto has recieved a lot of positive feedbacks.

The only downside to this product is its long term use which may affect the liver. Overall, Prosta Metto is an excellent supplement for prostate and urinary health.

Sources


http://www.body-soul-spirit-center.com/themes/kategorie/detail.php?artikelid=51&languageid=2

http://www.umm.edu/altmed/articles/saw-palmetto-000272.htm

http://www.mdidea.com/products/herbextract/sawpalm/data06.html

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