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Vitarin Supplement Facts

Learn more about the ingredients in Vitarin.
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 Vitarin Supplement Facts

 Serving Size:  3 Capsules
 Servings Per Container:  30



  Amount
Per Serving
Daily Value


  Vitamin C (Ascorbic Acid) 50 mg 83%

  Vitamin D (Cholecalciferol) 400 IU 100%

  Thiamin (Thiamin HCL) 1 mg 67%

  Vitamin B6 (Pyridoxine HCL) 2 mg 100%

  Calcium (Citrate)

147 mg 15%

  Magnesium (Oxide) 400 mg 100%

  Zinc (Sulfate) 3.2 mg 21%




  Boron (Amino Acid Chelate) 1 mg *

  Citrus Bioflavonoid Complex 300 mg *

  GABA 250 mg *


 *Daily Value Not Established



Other Ingredients: Vegetarian Capsule (Hypromellose), Cellulose, Magnesium Stearate.

Daily Dosage:As a dietary supplement, take two capsules in the morning and one capsule in the afternoon with 8 ounces of water. 45-60 days of continuous use is necessary for optimum results.

 

Vitarin Research:

Vitamin C- Vitamin C is required for the synthesis of collagen, an important structural component of blood vessels, tendons, ligaments, and bone. People suffering from CP can often dislocate a joint during a spasm or have scar tissue on the veins due to repeated needle sticks, so the production of collagen is very important to keep tendons, ligaments and blood vessles healthy.

Vitamin C also plays a key role in the synthesis of the neurotransmitter, norepinephrine. Neurotransmitters are essential to brain function and are known to affect mood; older individuals tend to have depression in conjuction with CP(26). Therefore, vitamin C’s positive effect on mood can be very beneficial to individuals suffering from CP. In addition, vitamin C is required for the synthesis of carnitine, a small molecule that is essential for the transport of fat to the power house of a cell, for conversion to energy(1).

We all know that Vitamin C is essential for a healthy immune system, but do you know why? This is because vitamin C is an antioxidant and even in the smallest amounts can protect extremely important molecules in the body such as protein, lipids, carbohydrates, DNA and RNA(1). Humans do not posses the ability to make their own source of vitamin C; therefore, it is essential that we supplement through vitamins and diet.

Vitamin D- Vitamin D is essential for the efficient utilization of calcium by the body (2). A Vitamin D deficiency can cause unexplained muscle pain and weakness(3) and is a known problem in people with CP. A study published by Pubmed proved that people, particularly those with CP, have deficencies of vitamin D and when supplemented can increase there levels and is not associated with hypocalcaemia or other adverse effects(4). Therefore, this would cut down on muscle pain and weakness. In a study of 150 consecutive patients in Minnesota for the evaluation of persistent, nonspecific musculoskeletal pain, 93% had serum 25(OH)D levels indicative of vitamin D deficiency (3).

Seizure medication may accelerate the metabolism of vitamin D, and vitamin D intake from diet and sunlight exposure may be reduced in CP patients, increasing the risk of fracture.(24) Assessing vitamin D status in children who are immobilized with CP should be a routine event with appropriate supplements being given to all affected children. The American Academy of Pediatrics recently suggested that all members of the population should receive 200IU/day of vitamin(25)

Thiamin- Thiamin is a water-soluble B vitamin, previously known as vitamin B1 or aneurine(5). Thiamin was also the first organic compund to be recognized in the 1930’s as a vitamin(6). Thiamin is a required coenzyme to several important enzymes in the body. A defeciency in Thiamin can cause neuropathy, muscle pain and weakness, cardiac distrubances, and neurological distrubances(5). A common “side effect” of CP is something called post-impairment syndorme(26), this is a combination of muscle pain and weakness the supplementation of thiamin in the diet may decrease muscle pain and weakness.

Vitamin B6- B6 is an extremely important vitamin in the body it effects everything from your nervous system, to your immune system, hormones and your DNA. Making sure you have enough B6 in your diet is essential to feeling healthy and energized as it also plays a key role in the sythesis of heme, which is the iron carrying componet of the blood(7).

Calcium- Calcuim is the most abundant mineral in the body about 99% of the calcium in the body is found in the bones and teeth, while the other one percent is found in the soft tissue and blood. Calicium is crucial to a healthy skeletal system(8). Not only is calcium important to the skeletal system but that one percent in the blood has a huge job. It is responsible for constriction and relaxation of blood vessels, nerve impulse transmission, muscle contraction, and the secretion of hormones(9).

Calcium is known for the prevention of osteoporosis; however, what most people don’t know is a very real and serious condition that often accompanies CP is something called osteopenia(26). Osteopenia is a condition that causes weakening of the bone and leads to fragile easy to break bones; calcium along with Vitamin D are essential to people with CP most definitly if the individual is of little to no weight bearing.

Magnesium- Magnesium is an essential mineral to the proper function of the human body. It plays a key role in several of our bodies systems such as bone health, cell communication, energy production, and synthesis of essentials molecules. Of the magnesium that exists in the body 60% of it is in the skeleton, 27% is in the muscle, 6-7% is found in other cells, and 1% is found outside the cells(10).

Zinc- Zinc is a trace element essential for all forms of life. The discovery of the need for zinc is relatively new; it was not discovered that this element was essential until 1961. It was then that doctors and researcher put together a link between low zinc diets and "adolescent nutritional dwarfism" this link was made in teenagers in the middle east(11). Since then, there have been many links between zinc insufficencies and debilitating diseases in delveloping contries(12). Zinc plays key roles in growth and development as well as neurological function, reproduction, and immune response(13).

The neurological role of Zinc is that of cell signaling; it has been found to influence the release of hormones and nerve impulse transmission. It has recently been found that zinc has a direct effect on apoptosis as well as many long term illnesses and diseases(14).

Boron- Is a trace element that has a direct effect on the absorption of calcium and magnesium(15) calcium and magnesium are essential to individuals suffering from CP, therefore boron is essential to make sure they are absorbed adequately. According to the USDA, boron is a trace mineral that helps bones develop and grow normally. Boron becomes especially important when there is not enough vitamin D in the diet. Boron may also prevent arthritis(16) a common side effect of CP. Decreased amounts of Boron have been shown to cause decreased electrical activity in the brain, as well as impaired hand eye coordination, and poor manual dexterity(17).

Citrus Bioflavonoid Complex- Bioflavonoid complex has been said to be a major boost to vitamin C(18). As well as having many vascular benefits such as healing ulcers and increasing blood flow(19,20). Citrus Bioflavonoid complex is an all around wonderful product that works in conjunction with vitamin C to ensure you receive the maximum benefits necessary.

GABA- GABA functions as a neurotransmitter helping nerve cells to communicate and lower stress. Research has shown that individuals with low levels of GABA are more susceptible to irritability, anxiety, and depression(21). This particular supplement has also proved to have effects on epilepsy and ADD(22,23). Epilepsy and depression are very common secondary diseases related to CP(26).

 

References:

1. Carr AC, Frei B. Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans. Am J Clin Nutr. 1999;69(6):1086-1107.

2. Holick MF. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr. 2004;79(3):362-371.

3. Plotnikoff GA, Quigley JM. Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain. Mayo Clin Proc. 2003;78(12):1463-1470.

4. Kilpinen-Loisa P, Nenonen H, Pihko H, Mäkitie O. High-dose vitamin D supplementation in children with cerebral palsy or neuromuscular disorder. Neuropediatrics. 2007 Aug;38(4):167-72.

5. Tanphaichitr V. Thiamin. In: Shils M, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore: Williams & Wilkins; 1999:381-389.

6. Rindi G. Thiamin. In: Ziegler EE, Filer LJ, eds. Present Knowledge in Nutrition. 7th ed. Washington D.C.: ILSI Press; 1996:160-166.

7. Leklem JE. Vitamin B6. In: Shils M, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore: Williams & Wilkins; 1999:413-422.

8. Weaver CM, Heaney RP. Calcium. In: Shils M, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore: Williams & Wilkins; 1999:141-155.

9. Food and Nutrition Board, Institute of Medicine. Calcium. Dietary Reference Intakes: Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, D.C.: National Academy Press; 1997:71-145.

10. Rude RK, Shils ME. Magnesium. In: Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ, eds. Modern Nutrition in Health and Disease. 10th ed. Baltimore: Lippincott Williams & Wilkins; 2006:223-247

11. Prasad AS, Halsted JA, Nadimi M. Syndrome of iron deficiency anemia, hepatosplenomegaly, hypogonadism, dwarfism, and geophagia. Am J Med. 1961;31:532-546

12. Prasad AS. Zinc deficiency in humans: a neglected problem. J Am Coll Nutr. 1998;17(6):542-543.

13. Cousins RJ. Zinc. In: Bowman BA, Russell RM, eds. Present Knowledge in Nutrition. 9th ed, Vol. 1. Washington, D.C.: ILSI Press; 2006:445-457.

14. Truong-Tran AQ, Ho LH, Chai F, Zalewski PD. Cellular zinc fluxes and the regulation of apoptosis/gene-directed cell death. J Nutr. 2000;130(5S Suppl):1459S-1466S.

15. Armstrong TA, Spears JW. Effect of dietary boron on growth performance, calcium and phosphorus metabolism, and bone mechanical properties in growing barrows. J Anim Sci. 2001 Dec;79(12):3120-7.
PMID: 11811468
16. Gaby AR. Natural treatments for osteoarthritis.Altern Med Rev. 1999 Oct;4(5):330-41. Review. PMID: 10559548

17. Penland JG. The importance of boron nutrition for brain and psychological function. Biol Trace Elem Res. 1998 Winter;66(1-3):299-317. Review.
PMID: 10050926

18. Middleton E Jr, Drzewiecki G, Tatum J. The effects of citrus flavonoids on human basophil and neutrophil function. Planta Med. 1987;53:325-328

19. Galley P, Thiollet M. A double-blind, placebo-controlled trial of a new veno-active flavonoid fraction (S 5682) in the treatment of symptomatic capillary fragility. Int Angiol. 1993;12:69-72.

20. Guilhou JJ, Dereure O, Marzin L, et al. Efficacy of Daflon 500 mg in venous leg ulcer healing: a double-blind, randomized, controlled versus placebo trial in 107 patients. Angiology. 1997;48:77-85.

21. Cavagnini F, Invitti C, Pinto M. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol 1980;93:149-54.

22. Rhodes ME, Frye CA. Actions at GABA(A) receptors in the hippocampus may mediate some antiseizure effects of progestins. Epilepsy Behav May 2005;6(3):320-7.

23. Vyazovskiy VV, Kopp C, Bosch G, et al. The GABA(A) receptor agonist THIP alters the EEG in waking and sleep of mice. Neuropharmacology Apr 2005;48(5):617-26.

24. Bischof F, Basu D, Pettifor JM. (2002) Pathological long-bone fractures in residents with cerebral palsy in a long-term care facility in South Africa. Dev Med Child Neurol 44: 119–122.

25. Greer FR. (2004) Issues in establishing vitamin D recommendations for infants and children. Am J Clin Nutr 80 (Suppl. 6): 1759S–1762S.

26. Cerebral Palsy: Hope Through Research. National Institute of Neurological
Disorders and Stroke (U.S.). NIH Publication No. 06-159 (July 2006). Retrieved on 2007-07-06.


FEATURED PRODUCT
VITARIN

VITARIN

Vitarin, a cerebral palsy remedy, contains a unique combination of vitamins and minerals specifically for helping the problems associated with CP.