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Listol Supplement Facts

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Learn more about the ingredients in the ADHD supplement Listol.
Listol Supplement Facts

  Serving Size: 6 Small Capsules
  Servings Per Container: 30

Per Serving
Daily Value

  Vitamin B6 (as Pyridoxine HCL) 10 mg 500%

  Calcium (as Calcium Carbonate) 250 mg 25%

  Iron (as Iron Citrate) 2.5 mg 14%

  Magnesium (as Magnesium Oxide) 300 mg 75%

  Zinc (as Zinc Oxide) 5 mg 33%

  Copper (as Copper Gluconate) 500 mcg 25%

  Phosphatidylserine 100 mg *

  Di-Methyl Glycine 75 mg *

  Glycine 500 mg *

  GABA Powder 250 mg *

  DMAE Bitartrate 350 mg *

  Huperzine A Extract (Huperzia serrata) (moss) 1 mg *

  Other Ingredients: Vegetarian Capsule (Hypromellose), Rice Powder, Magnesium Stearate.
  *Daily Value Not Established

Dosage and Directions: As an ADHD dietary supplement, adults and children over the age of 12, take 3 capsules twice daily immediately following a meal. Children under 12 take 3 capsules once daily, immediately following a meal.


Listol Research:

Vitamin B6. Pyridoxine is essential for the proper function of the nervous system, so it comes as no surprise that this vitamin can reduce central nervous system excitability in children.

Researchers conducted a clinical study where 52 hyperexcitable children were given a regimen of vitamin B6 and magnesium for 3-24 weeks. The results showed that in all patients, symptoms of hyperexcitability (physical aggressivity, instability, scholar attention, hypertony, spasm, myoclony) were reduced after 1 to 6 months of treatment (1)

Iron. Research indicates that iron deficiency is associated with attention-deficit/hyperactivity disorder in children.

Markers of iron status are significantly lower in children with ADHD than healthy controls (2). As well, lower serum values of ferritin are directly correlated with the severity of symptoms and cognitive deficits. Treatment with iron in children with ADHD has shown improvements in the Conners Rating Scale for Parents (3). Learn more about iron and ADHD.

Magnesium. In a study of 116 children with ADHD, magnesium deficiency was observed in 95% of the subjects. Analysis of the data showed a correlation between levels of magnesium and the quotient of development to freedom from distractibility (4).

A Supplementation with magnesium for six months in children who have ADHD and magnesium deficiency has demonstrated decreased hyperactivity in a controlled trial (5). Decreased hyperexcitability has also been established with magnesium and vitamin B6 supplementation (1).

Zinc. Another essential mineral, zinc, has also been linked to ADHD.

A study conducted to explore the relationship of zinc nutrition to the severity of attention-deficit/hyperactivity disorder (ADHD) symptoms in a middle-class American sample with well-diagnosed ADHD showed that serum zinc levels correlated with parent-teacher-rated inattention (6).

A double-blind, randomized placebo-controlled trial of supplementation with zinc plus methylphenidate (pharmaceutical treatment) for six weeks in children with ADHD concluded that Parent and Teacher Rating Scale scores improved when compared to placebo plus methylphenidate (7).

Another double-blind, randomized placebo-controlled supplementation trial of zinc sulfate alone demonstrated zinc was superior to placebo in reducing symptoms of hyperactivity, impulsivity, and impaired socialization in patients with ADHD, and was well tolerated (8). More information about ADHD and Zinc.

Copper. When supplementing with zinc, it is always important to take additional copper to prevent deficiency of this trace mineral, as zinc and copper compete for absorption.

Furthermore, copper levels are lower in children with hyperactivity (9).

Phosphatidylserine. An essential phospholipid, phosphatidylserine, can improve symptoms of ADHD. An in-office trial of phosphatidylserine supplementation for up to 4 months showed benefit in 90% of cases of ADHD treated in a physician’s office, most notably with learning and attention improvements (10, 11). Learn more about phosphatidylserine and ADHD.

Di-Methyl Glycine. Abnormal glucose metabolism is a proposed contributor to ADHD. Treatment with di-methyl glycine may improve symptoms of hypoglycemia, which can occur in some patients with ADHD.

Glycine. Glycine is an essential amino acid that is vital for the nervous system to function correctly. Glycine supplementation in animals has been shown to reduce hyperactivity through dopaminergic pathways (12,13). In one case study, oral treatment with glycine improved hyperactivity in a young boy (14).

GABA Powder. GABA pathways in the brain appear to play a role in certain cognitive disorders like ADHD. Researchers have proposed using pharmaceutical GABA enhancers to treat conditions, including ADHD (15). Learn more about ADHD and GABA.

DMAE Bitartrate. DMAE is a precursor for phosphatidylcholine, an essential phospholipid in the brain. Supplementation with DMAE has demonstrated improvements in hyperkinesis, an older term for ADHD (16). Learn more about DMAE and GABA. Learn more about ADHD and DMAE.

Huperzine A Extract. This natural compound is drawing much attention for its effects on cognitive function, enhancing memory, and treating cognitive deficits (17,18). A double-blind placebo-controlled trial of huperzine A supplementation in patients with cognitive deficits of Alzheimer’s type showed it is a safe and effective medicine, improving cognition, behavior, activities of daily living and mood (19).


1. Mousain-Bosc M et al. Magnesium VitB6 intake reduces central nervous system hyperexcitability in children. J Am Coll Nutr. 2004 Oct;23(5):545S-548S.

2. Konofal E et al. Iron deficiency in children with attention-deficit/hyperactivity disorder. Arch Pediatr Adolesc Med. 2004 Dec;158(12):1113-5.

3. Sever Y et al. Iron treatment in children with attention deficit hyperactivity disorder. A preliminary report. Neuropsychobiology. 1997 ;35(4) :178-80.

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