Renalis Supplement FactsLearn more about the ingredients in Renalis.
Daily Dosage: As a dietary supplement, take two capsules in the morning and one capsule in the evening with 8 ounces of water. Our suggested minimum serving is 3 capsules daily/maximum serving of 6 capsules daily. 45-60 days of continuous use is necessary for optimum results.
Renalis Research: Hydrangea (Hydrangea arborescens) - Hydrangea has mild diuretic activity and has traditionally been used to treat kidney stones and prevent their formation (1). In certain cases managed only by a physician, a botanical formula including hydrangea has been used to assist with passage of calcium oxalate or phosphate stones that are no larger than 5mm in diameter, and in patients who are in good health (2).
Chanca Piedra (Phyllanthus niruri) - An herb with a long historical tradition in South America for patients with kidney stones, Phyllanthus has a body of scientific evidence supporting its use. In sixty-nine patients who tend to form calcium kidney stones, administration of Phyllanthus capsules for three months reduced urinary calcium levels when compared to placebo (3). Another study showed an inhibitory effect of Phyllanthus extract on calcium oxalate crystal growth and aggregation in human urine, suggesting that it may interfere with the early stages of stone formation (4). Research has also shown that the extract is not toxic to kidney cells (5).
Aloe vera - Aloe is better known for its laxative and wound healing effects. However, aloe also is useful in patients who tend to form kidney stones. One of it constituents, emodin, has mild diuretic activity. As well, aloe binds calcium and can rapidly decrease the growth rate of calcium crystals in the urine (6).
Magnesium citrate - This form of magnesium has added benefit with both components exerting effects in patients prone to kidney stone formation (7,8). Magnesium increases the solubility of calcium in the urine and decreases its absorption leading to decreased formation of calcium oxalate (making up 90% of kidney stones). Citrate increases urinary magnesium citrate levels and decreases urinary oxalate. In patients with a history of kidney stones, magnesium should be taken regularly to exert an alkali loading effect, thereby reducing the chance of calculus formation (9). Patients with idiopathic calcium urolithiais (ICU) tend to have more acidic urine and lower levels of free citrate, making magnesium citrate the ideal supplement (10). It appears magnesium citrate is most effective when taken with meals.
Vitamin B-6 - In a study of over 85000 women, the results showed that lower levels of vitamin B6 are associated with increased risk of developing kidney stones (11). The authors suggest that large doses of this vitamin may reduce the incidence of kidney stone formation. Suboptimal levels of vitamin B6 lead to increased urinary levels of oxalate and resultant stone formation in some patients (12). Children with a history of kidney stones have benefited from supplementation with vitamin B6, thereby reducing levels of urinary oxalate resulting in no stone formation in a 1 year follow-up, as well as resolution of abdominal pain and blood in the urine (13). Supplementation in adults also reduces the risk of recurrent calcium-oxalate stone formation (14).
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